Darunavir: Mechanism of Action and Uses

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What is darunavir used for?

Darunavir is used with a pharmacokinetic booster (a medication that increases the amount of other medications in the body) such as ritonavir (Norvir) or cobicistat (Tybost), and other medications to treat human immunodeficiency virus (HIV) infection in adults and children 3 years of age and older.

Does darunavir cure HIV?

Darunavir is in a class of medications called protease inhibitors. It works by decreasing the amount of HIV in the blood. Although darunavir does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer.

Is darunavir a ritonavir or cobicistat?

Darunavir (brand name: Prezista) is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children. Darunavir is always used in combination with a pharmacokinetic enhancer — either ritonavir (brand name: Norvir) or cobicistat (brand name: Tybost) — and other HIV medicines.

Can darunavir cause liver problems?

Darunavir can cause serious, life-threatening side effects. These include liver problems, severe skin rash, allergic reactions, and drug interactions. Some people taking darunavir in combination with either ritonavir or cobicistat ( pharmacokinetic enhancers used with darunavir) may develop liver problems, which can be life-threatening.

What Is Darunavir

1. https://www.drugs.com/mtm/darunavir.html
2. https://en.wikipedia.org/wiki/Darunavir
3. https://go.drugbank.com/drugs/DB01264
4. https://clinicalinfo.hiv.gov/en/guidelines/pediatric-arv/darunavir
5. https://medlineplus.gov/druginfo/meds/a607042.html
6. https://www.nps.org.au/medicine-finder/darunavir-juno
7. https://www.healthdirect.gov.au/medicines/brand/amt,1044771000168101/darunavir-mylan
8. https://www.aidsmap.com/about-hiv/arv-factsheet/darunavir
9. https://my.clevelandclinic.org/health/drugs/18109-darunavir-tablets

Darunavir Information

1. https://www.ema.europa.eu/en/medicines/human/EPAR/darunavir-mylan