Benefits of GeneXpert Testing for Infectious Disease Management

GeneXpert is a molecular diagnostic platform that enables rapid and accurate testing for infectious diseases, including tuberculosis, COVID-19, and sexually transmitted infections, using automated cartridge-based technology.
Category
Diagnostic Device
Where to get
Available in hospitals, clinics, laboratories, and mobile testing units.
Applicable for
Infectious Diseases | Molecular Testing
Prepared by Shruti Sahoo, reviewed by Dr. Eugene Smith

GeneXpert FAQ


Image credit: info.cepheid.com

What is a GeneXpert test?

The GeneXpert assay has been widely reported in recent years as a type of nucleic acid assay. The GeneXpert test is more sensitive and accurate than traditional smear and culture methods and can detect Mycobacterium tuberculosis even in the presence of negative sputum smears.

What is GeneXpert (GX)?

1 Department of Pulmonary Medicine, Topiwala National Medical College & BYL Nair Hospital, Mumbai, Maharashtra, India. Introduction: GeneXpert (GX) is a novel, integrated, cartridge-based, nucleic acid amplification test with an established role for rapid diagnosis of Mycobacterium tuberculosis and detection of rifampicin resistance.

What is gene Xpert?

It is also called Gene Xpert because it works as its name. The GeneXpert system utilizes a unique technology called real-time polymerase chain reaction (PCR) to detect and analyze genetic material, such as DNA or RNA, in a biological sample.

How does GeneXpert work?

Point-of-care testing: GeneXpert is portable and can be deployed in decentralized settings, such as clinics or rural areas, as a point-of-care testing tool. It eliminates the need for sample transportation to centralized laboratories, reducing turnaround time, and improving patient access to timely diagnosis.

GeneXpert References

If you want to know more about GeneXpert, consider exploring links below:

What Is GeneXpert

  1. https://en.wikipedia.org/wiki/GeneXpert_MTB/RIF
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7718474/
  3. https://oncquestlabs.com/blog/genexpert-test/
  4. https://www.cepheid.com/content/dam/www-cepheid-com/documents/documents/301-training-materials/301-0739%20Rev%20%20D%20System%20User%20Training.pdf
  5. https://www.cdc.gov/tb/publications/factsheets/testing/xpert_mtb-rif.htm
  6. https://pubmed.ncbi.nlm.nih.gov/32706101/
  7. https://tdr.who.int/newsroom/news/item/17-10-2022-integrating-genexpert-molecular-testing-technology-in-national-health-systems-lessons-from-four-implementation-research-studies
  8. https://www.pih.org/article/why-genexpert-matters-pih-and-global-health
  9. https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(21)00613-7/fulltext

GeneXpert Information

  1. https://uat-content.cepheid.com/en-US/systems/genexpert-family-of-systems/genexpert-system.html
  2. https://web-support.cepheid.com/en_CA/systems/GeneXpert-Family-of-Systems/GeneXpert-System

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