Lincosamides - Antibiotics for Bacterial Infections

Lincosamides are a class of antibiotics that inhibit bacterial protein synthesis by binding to the 50S subunit of the ribosome.

Lincosamides FAQ

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What are lincosamides used for?

Lincosamides are a class of antibiotics that treat certain types of bacterial infections. These medications can be helpful against infections that are aggressive or resistant to other treatments. Clindamycin is the most common lincosamide used in humans. What are lincosamides? Lincosamides are a class of antibiotics.

What is lincosamide antibiotic?

lincosamide, any agent in a class of antibiotics that are derived from the compound lincomycin and that inhibit the growth of bacteria by blocking bacterial protein synthesis. Lincomycin, the first lincosamide, was isolated in 1962 from a soil bacterium ( Streptomyces lincolnensis ).

What does a lincosamide writer do?

They write new content and verify and edit content received from contributors. lincosamide, any agent in a class of antibiotics that are derived from the compound lincomycin and that inhibit the growth of bacteria by blocking bacterial protein synthesis.

Which lincosamide is derived from Streptomyces spp?

The lincosamides are naturally occurring compounds derived from Streptomyces spp. Clindamycin, approved in 1966, is the only lincosamide available in the U.S. and is a semisynthetic derivative of lincomycin.

How Lincosamides are recombined?

Lincosamides consist of a pyrrolidine ring linked to a pyranose moiety (methylthio-lincosamide) via an amide bond. Hydrolysis of lincosamides, specifically lincomycin, splits the molecule into its building blocks of the sugar and proline moieties. Both of these derivatives can conversely be recombined into the drug itself or a derivative.

What are lincosamides and clindamycin?

The two established members of the group of antibiotics known as the lincosamides, lincomycin and its semisynthetic derivative clindamycin, have a narrow antibacterial spectrum involving mostly Gram-positive species and some obligate anerobes, such as Bacteroides.