Liposomes - Innovative Drug Delivery Systems

Liposomes are spherical vesicles composed of lipid bilayers, used as carriers for drugs or nutrients due to their ability to encapsulate hydrophilic or hydrophobic substances.
Category
Carrier
Where to get
Produced in pharmaceutical companies, used in drug delivery research.
Applicable for
Prepared by Shruti Sahoo, reviewed by Dr. Eugene Smith

Liposomes FAQ

What does the name liposome mean?

The name liposome is derived from the two Greek words 'lipos,' meaning fat, and 'soma,' meaning body. Liposomes can vary in size from 0.025 micrometers (µm) up to 2.5 µm vesicles.

What are liposomes used for?

Liposomes are used as models for artificial cells. Liposomes can be used on their own or in combination with traditional antibiotics as neutralizing agents of bacterial toxins. Many bacterial toxins evolved to target specific lipids of the host cells membrane and can be baited and neutralized by liposomes containing those specific lipid targets.

What are liposomes made of?

Liposomes are composite structures made of phospholipids and may contain small amounts of other molecules.

What are the physico-chemical properties of liposomes?

The liposomes’ final organization, structure, and physico-chemical properties depends on the types, size, morphology, concentration, and charge of the constituent lipids, as well as the solution properties (such as the ionic strength, pH, temperature) [ 27, 28 ].

What are liposomes made out of?

Liposomes are primarily created from phospholipids such as soybean phosphati-dylcholine or synthetic dialkyl or trialkyl lipids . Incorporation of cholesterol into liposomes is indispensable since cholesterol modulates membrane permeability, changes uidity, and improves the stability of

What is a liposome in chemistry?

Keywords: cholesterol; compounds; lipids; liposome; stability. Liposomes are essentially a subtype of nanoparticles comprising a hydrophobic tail and a hydrophilic head constituting a phospholipid membrane.

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