Maraviroc - Treatment for HIV

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How does maraviroc work?

Maraviroc is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5. Maraviroc is an entry inhibitor and works by blocking HIV from entering human cells.

Is Maraviroc a cure for HIV?

This lowers your chance of getting HIV complications (such as new infections, cancer) and improves your quality of life. Maraviroc belongs to a class of drugs known as entry inhibitors. It works by blocking the HIV virus from infecting healthy immune cells (T-cells).Maraviroc is not a cure for HIV infection.

Is Maraviroc a chemokine receptor antagonist?

Maraviroc (brand-named Selzentry, or Celsentri outside the U.S.) is a chemokine receptor antagonist drug developed by the drug company Pfizer that is designed to act against HIV by interfering with the interaction between HIV and CCR5.

Is maraviroc an entry inhibitor?

Maraviroc is an entry inhibitor. Specifically, maraviroc is a negative allosteric modulator of the CCR5 receptor, which is found on the surface of certain human cells. The chemokine receptor CCR5 is an essential co-receptor for most HIV strains and necessary for the entry process of the virus into the host cell.

Does maraviroc cure HIV?

Maraviroc is in a class of medications called HIV entry and fusion inhibitors. It works by decreasing the amount of HIV in the blood. Although maraviroc does not cure HIV, it may decrease your chance of developing acquired immunodeficiency syndrome (AIDS) and HIV-related illnesses such as serious infections or cancer.

Can I use maraviroc If I have CCR5 tropic HIV?

It should only be used by people who have a type of HIV which is ‘CCR5 tropic’. Maraviroc works by blocking the CCR5 receptor, which HIV uses to get into blood cells. If you are considering using maraviroc, your HIV clinic will run a tropism test to see whether you have CCR5-tropic HIV.

What Is Maraviroc

1. https://en.wikipedia.org/wiki/Maraviroc
2. https://www.drugs.com/mtm/maraviroc.html
3. https://medlineplus.gov/druginfo/meds/a607076.html
4. https://clinicalinfo.hiv.gov/en/drugs/maraviroc/patient
5. https://go.drugbank.com/drugs/DB04835
6. https://www.aidsmap.com/about-hiv/arv-factsheet/maraviroc
7. https://patient.info/medicine/maraviroc-tablets-for-hiv-celsentri
8. https://www.mayoclinic.org/drugs-supplements/maraviroc-oral-route/description/drg-20071288
9. https://www.webmd.com/drugs/2/drug-148854/maraviroc-oral/details

Maraviroc Information

1. https://www.healthdirect.gov.au/medicines/medicinal-product/aht,21190/maraviroc
2. https://australianprescriber.tg.org.au/articles/maraviroc.html
3. https://www.medicine.com/drug/maraviroc/hcp