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Is tetracycline a glycylcycline?

Tigecycline, sold under the brand name Tygacil, is a tetracycline antibiotic medication for a number of bacterial infections. It is a glycylcycline administered intravenously.

What is tigecycline used for?

Tigecycline is used to treat many different bacterial infections of the skin or the digestive system, as well as pneumonia. Tigecycline should be used only for infections that cannot be treated with other medicines. Tigecycline may also be used for purposes not listed in this medication guide.

What is tigecycline a glycylcycline?

, PharmD, University of Washington School of Pharmacy Tigecycline is the only antibiotic in an antibiotic class called glycylcyclines, which are related to tetracyclines . Tigecycline works by preventing bacteria from producing proteins they need to grow and multiply.

Is tigecycline an antibiotic?

[ PubMed] [ CrossRef] [ Google Scholar] 147. Dryden M (2013) Tigecycline: an antibiotic for the twenty-first century. Journal of Antimicrobial Chemotherapy 68 (suppl_2):ii3-ii4 [ PubMed] 148.

How does tigecycline work?

Tigecycline is a broad-spectrum antibiotic that acts as a protein synthesis inhibitor. It exhibits bacteriostatic activity by binding to the 30S ribosomal subunit of bacteria and thereby blocking the interaction of aminoacyl-tRNA with the A site of the ribosome.

What infections can tigecycline treat?

Tigecycline can treat complicated skin and structure infections caused by; Escherichia coli, vancomycin-susceptible Enterococcus faecalis, methicillin-resistant Staphylococcus aureus (MRSA), Streptococcus agalactiae, Streptococcus anginosus grp., Streptococcus pyogenes, Enterobacter cloacae, Klebsiella pneumoniae, and Bacteroides fragilis.

Is tigecycline a glycylcycline antibiotic?

Tigecycline is a glycylcycline antibiotic that covers MRSA and Gram-negative organisms:

Is tigecycline a tetracycline?

Tigecycline is a chemically modified minocycline (9-t-butylglycylamido derivative of minocycline) [ 6, 9 ]. Compared with other tetracyclines, tigecycline’s extended, wide-range antibiotic activity is due to a main backbone of minocycline with an N-alkyl-glycylamido side chain addition to the C9 carbon of the “D” tetracycline ring [ 6, 9 ].

What Is Tigecycline

1. https://en.wikipedia.org/wiki/Tigecycline
2. https://www.drugs.com/mtm/tigecycline.html
3. https://go.drugbank.com/drugs/DB00560
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785128/
5. https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/tigecycline
6. https://academic.oup.com/jac/article/56/4/611/769325
7. https://www.msdmanuals.com/home/infections/antibiotics/tigecycline
8. https://medlineplus.gov/druginfo/meds/a614002.html

Tigecycline Information

1. https://reference.medscape.com/drug/tygacil-tigecycline-342527
2. https://www.healthdirect.gov.au/medicines/medicinal-product/aht,20432/tigecycline