Verigene System - Molecular Diagnostics Platform

Image credit: techno-path.com

What is Verigene® System?

The VERIGENE® System is a simple to use, highly accurate multiplex in vitro diagnostic platform thatrapidly detects infectious pathogens and drug resistance markers, enabling clinicians to deliver timely andtargeted therapy for some of the most complex, costly, and deadly infectious diseases. Available and supported by TECHNOPATH.

What is a Verigene blood culture ID system?

The Verigene blood culture ID system differs from FilmArray in that there are two separate panels – one for gram-negative and one for gram-positive bacteria, and that there are no targets for yeast on these panels. One advantage of this approach is that analysis of more resistance genes can be performed in the multiplex reactions.

What is a Verigene micro-array?

Verigene is a DNA micro-array which allows for prompt characterization of a positive blood culture (including detection of specific bacterial species and resistance genes). Verigene has proved to have high sensitivity and specificity for gram-positive and gram-negative cultures, with an impressive and rapidly growing evidence basis.

Is Verigene a good antibiotic?

Verigene has proved to have high sensitivity and specificity for gram-positive and gram-negative cultures, with an impressive and rapidly growing evidence basis. Prompt evaluation for methicillin or vancomycin resistance facilitates rapid transition from empiric to definitive antibiotics.

Does Verigene identify pathogens with high sensitivity and specificity?

The literature is strongly positive regarding the ability of Verigene to identify pathogens with high sensitivity (~97%) and specificity (~99.5%). 1–3 This has been demonstrated among adult and pediatric patients, at a range of institutions across different countries.

How much does a Verigene analyzer cost?

Thus, Verigene provides a bit of a sneak peek at the bacteria’s identity. Traditional culture methods will return 1-2 days later, providing a double-check of the Verigene results. The initial acquisition cost of the Verigene analyzer is considerable (~$20,000). Subsequently, each assay costs roughly $50-100.

What is Verigene ® Clostridium difficile?

VERIGENE ® Clostridium difficile is a multiplexed, qualitative test for the rapid detection of toxin A (tcdA), toxin B (tcdB), and tcdC gene sequences of toxigenic C. difficile and for presumptive identification of PCR ribotype 027 strains from unformed (liquid or soft) stool specimens.

What Is Verigene System

1. https://us.diasorin.com/en/molecular-diagnostics/tools/verigene-system
2. https://www.youtube.com/watch?v=gh9QKKAOheg
3. https://int.diasorin.com/en/molecular-diagnostics/kits-reagents/verigene-gram-positive-blood-culture-test-bc-gp
4. https://emcrit.org/pulmcrit/verigene/
5. https://www.techno-path.com/product/verigene-system/
6. https://www.cap.org/member-resources/articles/rapid-molecular-panels-for-the-identification-of-bloodstream-pathogens