Optimizing Antibiotic Regimens for Effective Treatment

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What is the pharmacology of antibiotics?

Antibiotics are compounds that target bacteria and, thus, are intended to treat and prevent bacterial infections. The pharmacology behind antibiotics includes destroying the bacterial cell by either preventing cell reproduction or changing a necessary cellular function or process within the cell.

What are antibiotics & anti-infectives?

From treatments for painful strep throat or ear infections as a child, to burning urinary tract infections or itchy skin infections as an adult, antibiotics are one of the most highly utilized and important medication classes we have in medicine. Understanding the vast world of antibiotics and anti-infectives is no easy task.

What are the new antibiotic guidelines?

The Antibiotic Guidelines have been extensively revised and include more content than ever. They provide practical advice on managing a wide range of infections, from self-limiting infections usually managed in primary care (eg acute bronchitis, acute otitis media) to severe infections requiring treatment in hospital (eg meningitis, sepsis).

What should a prescriber consider when prescribing antibiotics?

Prescribers should consider the harm–benefit profile of a drug in each patient (eg consider potential drug interactions). Antibiotics that are overused in primary care include amoxicillin+clavulanate, cefalexin, cefaclor, roxithromycin and erythromycin. Antibiotic treatment is required rarely—most cases are viral.

What Is Antibiotic Regimens

1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031442/
2. https://www.mayoclinicproceedings.org/article/S0025-6196(11)63398-3/fulltext
3. https://www.msdmanuals.com/en-au/home/infections/antibiotics/overview-of-antibiotics
4. https://www.drugs.com/article/antibiotics.html
5. https://www.tg.org.au/wp-content/uploads/DownloadableWhatsNewAntibiotic2019.pdf
6. https://www.sciencedirect.com/science/article/pii/B9780323695787000041
7. https://www1.racgp.org.au/ajgp/2022/january-february/better-antibiotic-prescribing
8. https://www.healthdirect.gov.au/antibiotics

Antibiotic Regimens Information

1. https://www.safetyandquality.gov.au/sites/default/files/2020-11/therapeutic_guidelines_-_antibiotic_prescribing_in_primary_care_free_table.pdf
2. https://www.cochranelibrary.com/web/cochrane/content?templateType=information&urlTitle=%2Fcdsr%2Fdoi%2F10.1002%2F14651858.CD009880.pub3&doi=10.1002%2F14651858.CD009880.pub3&type=cdsr&contentLanguage=