Understanding Immunosuppression and Its Uses
Immunosuppression involves the weakening of the immune system's response, often for medical reasons such as preventing organ rejection in transplant patients or treating autoimmune diseases.
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Side Effects Of Immunosuppressive Therapy | Future Trends In Immunomodulation Therapies | Immunosuppressive Drugs | Immune System Suppression
Prepared by Shruti Sahoo, reviewed by Dr. Eugene Smith
Immunosuppression FAQ
Is CNI a nonimmunosuppressive mechanism for glomerular disease?
One potential nonimmunosuppressive mechanism that could explain CNI efficacy in glomerular disease is the ability to inhibit synaptopodin degradation in the podocyte, thereby stabilizing the actin cytoskeleton and reducing proteinuria ( 20 ).
How does IL-17 affect autoimmune disease?
IL-17 functions to increase inflammatory cell migration by stimulating chemokine release, and it increases APC activity to enhance adaptive immune responses. IL-17 has been shown to be a key mediator of injury in a number of autoimmune diseases, including ankylosing spondylitis, psoriasis, and multiple sclerosis (MS).
Immunosuppression References
If you want to know more about Immunosuppression, consider exploring links below:
What Is Immunosuppression
- https://www.verywellhealth.com/different-causes-of-immunosuppression-explained-4047405
- https://www.news-medical.net/health/What-is-Immunosuppression.aspx
- https://patient.info/allergies-blood-immune/immune-system-diseases/immune-suppression
- https://my.clevelandclinic.org/health/treatments/10418-immunosuppressants
- https://en.wikipedia.org/wiki/Immunosuppression
- https://www.osmosis.org/answers/suppressed-immune-system
- https://www.britannica.com/science/immunosuppression
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