Carbapenem Antibiotics: Mechanism and Uses

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Are carbapenems a bactericidal antibiotic?

Carbapenems are parenteral bactericidal beta-lactam antibiotics that have an extremely broad spectrum. They are active against Proteeae Infections The Proteeae are normal fecal flora that often cause infection in patients whose normal flora have been disturbed by antibiotic therapy.

What are carbapenems?

Carbapenems are a group of drugs in the beta-lactam antibiotic class (β-lactam antibiotics). Other medications in the beta-lactam class include popular antibiotics such as Keflex (cephalexin), amoxicillin, and Augmentin .

How do carbapenems work?

Carbopenems are a class of drugs used to treat a wide variety of bacterial infections (including Escherichia coli , Klebsiella pneumoniae, and Enterobacter cloaca) of the skin, lungs, stomach, pelvis , urinary tract, and kidneys.

What is carbapenem ertapenem?

The carbapenem ertapenem is one of several first-line agents recommended by the Infectious Disease Society of America for the empiric treatment of community-acquired intra-abdominal infections of mild-to-moderate severity. Agents with anti-pseudomonal activity, including doripenem, imipenem, and meropenem, are not recommended in this population.

What Is Carbapenem

1. https://www.drugs.com/drug-class/carbapenems.html
2. https://en.wikipedia.org/wiki/Carbapenem
3. https://www.rxlist.com/how_do_carbapenems_work/drug-class.htm
4. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3195018/
5. https://www.merckmanuals.com/professional/infectious-diseases/bacteria-and-antibacterial-drugs/carbapenems
6. https://www.singlecare.com/drug-classes/carbapenems
7. https://www.bmj.com/content/344/bmj.e3236
8. https://www.msdmanuals.com/en-sg/home/infections/antibiotics/carbapenems

Carbapenem Information

1. https://www.safetyandquality.gov.au/sites/default/files/2020-09/cpe_for_clinicians_sept_2020.pdf