Understanding Multidrug-resistant Infections

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Are multidrug resistant bacteria causing community-acquired infections?

Multidrug resistant (MDR) bacteria are one of the most important current threats to public health. Typically, MDR bacteria are associated with nosocomial infections. However, some MDR bacteria have become quite prevalent causes of community-acquired infections.

What is multidrug resistance?

This is also called cross-resistance. Infections with multidrug-resistant bacteria are hard to treat since few or even no treatment options remain. In some cases health care providers have to use antibiotics that are more toxic for the patient. Multidrug-resistance facilitates spread of antibiotic resistance.

Which microorganisms exhibit multi-drug resistance?

These microorganisms employ several mechanisms in attaining multi-drug resistance: Many different bacteria now exhibit multi-drug resistance, including staphylococci, enterococci, gonococci, streptococci, salmonella, as well as numerous other Gram-negative bacteria and Mycobacterium tuberculosis.

What is multidrug-resistant bacteria?

Some bacteria are resistant to many different antibiotics; they are multidrug-resistant. Multidrug-resistant bacteria can be difficult to treat and facilitates spread of antibiotic resistance. When a single bacterium is resistant to more than one antibiotic it is said to be multidrug-resistant. This can occur in two distinct ways.

What is a multidrug-resistant bacteria?

Multidrug-resistant (MDR) bacteria that are commonly associated with health care cause a substantial health burden. Updated national estimates for this group of pathogens are needed to inform public health action.

Are multidrug-resistant bacteria dangerous?

Multidrug-resistant bacteria (MDR) that are deadly pathogenic are rising day by day and pose a very serious threat to human health. Earlier, these types of antibiotic-resistant bacterial strains were rare and limited to only nosocomial-acquired infections, but nowadays, they have become very common.

How common are multidrug-resistant infections in health care?

Approximately two thirds of those deaths were associated with infections caused by multidrug-resistant (MDR) organisms that are commonly associated with health care.

What Is Multidrug-resistant Infections

1. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9633024/
3. https://www.cdc.gov/hai/mdro-guides/index.html
4. https://en.wikipedia.org/wiki/Multiple_drug_resistance
5. https://www.reactgroup.org/toolbox/understand/antibiotic-resistance/multidrug-resistant-bacteria/
6. https://www.nejm.org/doi/full/10.1056/NEJMoa1914433

Multidrug-resistant Infections Information

1. https://link.springer.com/article/10.1007/s00284-022-03061-7
2. https://academic.oup.com/cid/article/77/9/e46/7280428