Metronidazole: Uses, Dosage, Side Effects

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How does metronidazole work?

Metronidazole is thought to work by first diffusing into the cytoplasm of the anaerobic bacteria where it is then activated and reduced into a short-lived nitroso free radical which can interact with DNA, causing a loss of the helical DNA structure, strand breakage, and bacterial death.

How long can you take metronidazole?

Metronidazole is usually given for up to 10 days in a row. You may need to repeat this dosage several weeks later. Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication.

What are the side effects of metronidazole?

Constipation. Other side effects of metronidazole may include allergic reactions: such as itching, hives (urticaria), flushing of the skin, red skin rash that can be widespread, blisters and separation of skin layers, nasal congestion, dryness of the mouth and vagina, and fever. Abnormal heart rhythms (QT prolongation) may also occur.

How do you take metronidazole?

Take metronidazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Shake the oral suspension well before each use to mix the medication evenly. Use a dosing spoon, oral syringe, or measuring cup to measure the correct amount of medication.

What is metronidazole used for?

What is metronidazole? Metronidazole is an antibiotic that may be used to treat certain infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream. Symptomatic trichomoniasis (a sexually transmitted infection) in adults that has been confirmed by culture or wet smear test

Is metronidazole cytotoxic?

StatPearls [Internet]. Last Update: June 26, 2023. Metronidazole is one of the mainstay drugs for the treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. It is cytotoxic to facultative anaerobic microorganisms.

Why is metronidazole used to treat bacterial vaginosis?

These types of organisms often cause infections in areas of the body such as the gums, pelvic cavity and tummy (stomach or intestines) because they do not need oxygen to grow and multiply. Metronidazole is commonly prescribed to treat an infection called bacterial vaginosis.

Where can I find information on Metronidazole?

For more information, visit Therapeutic Goods Administration (TGA). More information is available on metronidazole including side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information.

What Is Metronidazole

1. https://www.drugs.com/metronidazole.html
2. https://www.medicalnewstoday.com/articles/metronidazole-oral-tablet
3. https://en.wikipedia.org/wiki/Metronidazole
4. https://medlineplus.gov/druginfo/meds/a689011.html
5. https://www.webmd.com/drugs/2/drug-6426/metronidazole-oral/details
6. https://www.mayoclinic.org/drugs-supplements/metronidazole-oral-route/description/drg-20064745
7. https://www.nhs.uk/medicines/metronidazole/
8. https://www.healthdirect.gov.au/medicines/medicinal-product/aht,21161/metronidazole
9. https://www.everydayhealth.com/drugs/metronidazole
10. https://www.msdmanuals.com/en-au/professional/infectious-diseases/bacteria-and-antibacterial-drugs/metronidazole-and-tinidazole

Metronidazole Information

1. https://patient.info/medicine/metronidazole-for-infection-flagyl
2. https://www.ncbi.nlm.nih.gov/books/NBK539728/