Tenofovir - Uses and Side Effects

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What is tenofovir used for?

Written by Cerner Multum. What is tenofovir? Tenofovir is an antiviral medicine that is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Tenofovir is not a cure for HIV or AIDS. Tenofovir is for use in adults and children at least 2 years old and weighing at least 22 pounds (10 kilograms).

What class of drug is tenofovir?

Tenofovir belongs to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs). It’s also a hepatitis B virus reverse transcriptase inhibitor (RTI). A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

How is tenofovir formed?

Tenofovir is formed when the diethyl phosphonate group is converted to its acid using trimethylsilyl chloride in the presence of sodium bromide, a further refinement of the original manufacturing route.

How is tenofovir activated?

Tenofovir activation is performed by a bi-phosphorylation which in order forms the biologically active compound, tenofovir biphosphate. 1 This metabolic activation has been shown to be performed in hepG2 cells and human hepatocytes. 8 Tenofovir is eliminated in the urine by tubular secretion and glomerular filtration.

Is tenofovir a generic drug?

Tenofovir oral tablet is available as generic drug and as a brand-name drug. Brand name: Viread, Vemlidy. Tenofovir comes in two forms: an oral tablet and an oral powder. Tenofovir oral tablet is approved to treat HIV infection and chronic hepatitis B virus infection. What is tenofovir? Tenofovir is a prescription drug.

What Is Tenofovir

1. https://www.drugs.com/mtm/tenofovir.html
2. https://www.healthline.com/health/drugs/tenofovir-oral-tablet
3. https://en.wikipedia.org/wiki/Tenofovir_disoproxil
4. https://medlineplus.gov/druginfo/meds/a602018.html
5. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7163232/
6. https://www.everydayhealth.com/drugs/tenofovir
7. https://www.healthdirect.gov.au/medicines/brand/amt,1465071000168102/tenofovir-sandoz
8. https://clinicalinfo.hiv.gov/en/drugs/tenofovir-disoproxil-fumarate/patient
9. https://www.mayoclinic.org/drugs-supplements/tenofovir-oral-route/proper-use/drg-20066221
10. https://www.goodrx.com/tenofovir/what-is

Tenofovir Information

1. https://patient.info/medicine/tenofovir-for-hepatitis-b-infection-viread-vemlidy
2. https://go.drugbank.com/drugs/DB14126
3. https://www.tga.gov.au/sites/default/files/auspar-tenofovir-disoproxil-fumarate-161110-pi.pdf