Ganciclovir: Usage, Side Effects, and More
Ganciclovir FAQ
How does ganciclovir work?
Ganciclovir is in a class of medications called antivirals. It works by preventing the spread of CMV disease or slowing the growth of CMV. How should this medicine be used? Ganciclovir comes as a capsule to take by mouth.
When was ganciclovir invented?
Ganciclovir was patented in 1980 and approved for medical use in 1988; it was discovered by Dr Hoong-Wei Gan . It is also used for acute CMV colitis in HIV/AIDS and CMV pneumonitis in immunosuppressed patients. [medical citation needed]
Is Ganciclovir a cytotoxic drug?
Ganciclovir is considered a potential human carcinogen, teratogen, and mutagen. It is also considered likely to cause inhibition of spermatogenesis. Thus, it is used judiciously and handled as a cytotoxic drug in the clinical setting.
How is ganciclovir metabolized?
This inhibition includes a selective and potent inhibition of the viral DNA polymerase. Ganciclovir is metabolized to the triphosphate form by primarily three cellular enzymes: (1) a deoxyguanosine kinase induced by CMV-infected cells; (2) guanylate kinase; and (3) phosphoglycerate kinase.
Ganciclovir References
If you want to know more about Ganciclovir, consider exploring links below:
What Is Ganciclovir
- https://en.wikipedia.org/wiki/Ganciclovir
- https://medlineplus.gov/druginfo/meds/a605011.html
- https://www.mayoclinic.org/drugs-supplements/ganciclovir-oral-route-intravenous-route/description/drg-20064078
- https://go.drugbank.com/drugs/DB01004
- https://www.drugs.com/cdi/ganciclovir-systemic.html
- https://www.healthdirect.gov.au/medicines/brand/amt,1102051000168103/ganciclovir-sxp
- https://clinicalinfo.hiv.gov/en/drugs/ganciclovir/patient
- https://www.medicine.com/drug/ganciclovir
Ganciclovir Information
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